LEADERSHIP
Our Team
  • Michiel Van Speybroeck
    Founder & CEO

    Driven by a fascination for drug delivery and a passion for providing top-level customer service, Michiel founded Harpago in 2021. Over the past decade, Michiel has held a variety of technical and commercial leadership roles in the pharmaceutical contract development and manufacturing industry, including the positions of CDO at SeraNovo, CTO at Ardena and CSO at Formac.


    Drug solubility enhancement has been the overarching theme in Michiel's career. He conducted his doctoral and post-doctoral studies in this area, and during his time in industry, his teams have progressed over 30 formulations for poorly water-soluble compounds from discovery to first-in-human studies.

  • René Holm
    Scientific Advisor
    René is professor in pharmaceutical physical chemistry at the University of Southern Denmark. Prior to his career in academia, René held senior scientific roles in the innovator pharmaceutical industry, including the position of Senior Director, Drug Product Development - Liquids & Parenterals at The Janssen Pharmaceutical Companies of Johnson & Johnson and the function of Senior Director, Pharmaceutical Science at Lundbeck. He has (co-)authored over 240 original articles in peer-reviewed publications and is inventor on over 20 patents and patent applications.

    René provides scientific advice to Harpago in the areas of developability, preformulation and formulation design.
  • Patrick Augustijns
    Scientific Advisor
    Patrick is professor in biopharmaceutics at the University of Leuven, Belgium. His research focuses on the biorelevant profiling of intestinal drug absorption, covering all underlying processes including dissolution, precipitation, degradation and permeation. One of his lab’s major research topics involves the study of in vivo drug and formulation behaviour via the aspiration and detailed characterization of human gastrointestinal fluids. Patrick is (co-)author of over 300 peer-reviewed publications.

    Patrick advises Harpago in the areas of biopredictive solubility, dissolution and permeability profiling.

  • Maarten Van Speybroeck
    Engineering & Financial Advisor
    Maarten is a serial entrepreneur with a track record of success in the technology industry. In 2008, he co-founded the geospatial technology company Gatewing, which was acquired by Trimble Navigation in 2012. In 2015, he co-founded the security wearables company Ticto, which was acquired by RightCrowd in 2018.

    Maarten holds a Master's degree in mechanical engineering from Ghent University. He coordinates Harpago's automation and laboratory informatics projects. Maarten also has a keen interest in corporate finance and helps in setting out Harpago's long-term financial strategy.


Discuss your solubility challenge
If you would like to learn more about our unique approach to solubility enhancement, you can reach out to one of our experts here. We are happy to make an assessment of the developability of your compound and to propose a suitable formulation development trajectory.